K2753

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K2753

Sigma

 

(±)-Ketamine hydrochloride

solid

Synonym:(±)-2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone hydrochloride
CAS Number:1867-66-9
Linear Formula:C13H16ClNO · HCl
Molecular Weight:274.19
EC Number:217-484-6
MDL number:MFCD00051420
PubChem Substance ID:24896222

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Description

Biochem/physiol ActionsSelective NMDA glutamate receptor antagonist; veterinary anesthetic.

Properties

formsolid
drug controlUSDEA Schedule III; stupéfiant; regulated under CDSA - not available from Sigma-Aldrich Canada
color white
solubilityH2O: 200 mg/mL
storage temp.2-8°C

Safety

Personal Protective Equipmentdust mask type N95 (US), Eyeshields, Faceshields, Gloves
Hazard CodesXn
Risk Statements22-36/37/38
Safety Statements26
WGK Germany3
RTECSGW1400000

References

referencePallers, et al., Effects of ketamine, a noncompetitive NMDA antagonist, on the acquisition of the lever-press response in rats. Physiol. Behav. 57, 389, (1995) Abstract
 Sato, et al., Ketamine inhibits the tonic response to carbachol and histamine in the guinea pig trachea. Eur. J. Anaesthesiol. 15, 486, (1998) Abstract
 Davidson, et al., Intraplantar injection of dextrorphan, ketamine or memantine attenuates formalin-induced behaviors. Brain Res. 785, 136, (1998) Abstract