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K2753
Sigma
(±)-Ketamine hydrochloride
solid
| Synonym: | (±)-2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone hydrochloride |
| CAS Number: | 1867-66-9 |
| Linear Formula: | C13H16ClNO · HCl |
| Molecular Weight: | 274.19 |
| EC Number: | 217-484-6 |
| MDL number: | MFCD00051420 |
| PubChem Substance ID: | 24896222 |
Description
| Biochem/physiol Actions | Selective NMDA glutamate receptor antagonist; veterinary anesthetic. |
Properties
| form | solid |
| drug control | USDEA Schedule III; stupéfiant; regulated under CDSA - not available from Sigma-Aldrich Canada |
| color | white |
| solubility | H2O: 200 mg/mL |
| storage temp. | 2-8°C |
Safety
| Personal Protective Equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
| Hazard Codes | Xn |
| Risk Statements | 22-36/37/38 |
| Safety Statements | 26 |
| WGK Germany | 3 |
| RTECS | GW1400000 |
References
| reference | Pallers, et al., Effects of ketamine, a noncompetitive NMDA antagonist, on the acquisition of the lever-press response in rats. Physiol. Behav. 57, 389, (1995) Abstract |
| Sato, et al., Ketamine inhibits the tonic response to carbachol and histamine in the guinea pig trachea. Eur. J. Anaesthesiol. 15, 486, (1998) Abstract | |
| Davidson, et al., Intraplantar injection of dextrorphan, ketamine or memantine attenuates formalin-induced behaviors. Brain Res. 785, 136, (1998) Abstract |






